Ace Antibody

Code CSB-PA001154XA01DLU
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:Ace Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ace Antibody Polyclonal antibody
Uniprot No.
Target Names
Ace Antibody
Alternative Names
Acetylcholinesterase (AChE) (EC 3.1.1.7) [Cleaved into: Acetylcholinesterase 16 kDa subunit; Acetylcholinesterase 55 kDa subunit] Ace CG17907
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ace protein (44-293aa)
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Rapidly hydrolyzes choline released into the synapse. It can hydrolyze butyrylthiocholine.
Gene References into Functions
  1. 1 engineered disulfide bridge, I327C/D375C increased stability to heat denaturation, urea, & organic solvents & provided protease resistance. The new disulfide bridge links the N-terminal domain (first 356 aa) to the C-terminal domain. PMID: 16686937
  2. Results provide insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge. PMID: 18422651
  3. kinetic studies show that it affects interactions with peripheral ligands and the entrance of some of the bulkier substrates PMID: 18439026
  4. molecular dynamics simulation reveals the insecticidal resistance mechanism of AChE and its mutation PMID: 19263097
Subcellular Location
Cell junction, synapse. Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane of the neuronal cholinergic synapses by a GPI-anchor.
Protein Families
Type-B carboxylesterase/lipase family
Database Links

KEGG: dme:Dmel_CG17907

STRING: 7227.FBpp0289713

UniGene: Dm.1179

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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