pamn-1 Antibody

Code CSB-PA306875XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pamn-1 Polyclonal antibody
Uniprot No.
Target Names
pamn-1
Alternative Names
pamn-1 antibody; T19B4.1Probable peptidyl-glycine alpha-amidating monooxygenase pamn-1 antibody; PAM) [Includes: Probable peptidylglycine alpha-hydroxylating monooxygenase antibody; PHM antibody; EC 1.14.17.3); Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase antibody; EC 4.3.2.5 antibody; Peptidylamidoglycolate lyase antibody; PAL)] antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pamn-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
Subcellular Location
Secreted.
Protein Families
Peptidyl-alpha-hydroxyglycine alpha-amidating lyase family; Copper type II ascorbate-dependent monooxygenase family
Database Links

KEGG: cel:CELE_T19B4.1

STRING: 6239.T19B4.1

UniGene: Cel.21030

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