aurB Antibody

Code CSB-PA002458XA01DLU
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) aurB Polyclonal antibody
Uniprot No.
Target Names
aurB
Alternative Names
ial antibody; CG6620 antibody; Aurora kinase B antibody; EC 2.7.11.1 antibody; IPL1/Aurora-like protein kinase antibody; Serine/threonine-protein kinase Ial antibody; Serine/threonine-protein kinase aurora-B antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) aurB protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates mei-S332 within residues 124-126 and stabilizes its association with centromeres during meiosis.
Gene References into Functions
  1. Regulation of Polo by Aurora B and Map205 is required for cytokinesis. PMID: 25332165
  2. We propose that mutual inhibitions between Aurora B and Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst. PMID: 23948252
  3. Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis. PMID: 20804174
  4. Aurora B interacts with and requires the Cdc37/Hsp90 complex for its stability. PMID: 12374737
  5. This protein accumulates at the mid-zones of chromosome-free spindles. PMID: 12654903
  6. INCENP binds to the cohesion protector protein MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase. PMID: 16824953

Show More

Hide All

Subcellular Location
Chromosome. Cytoplasm, cytoskeleton. Midbody. Note=Meiotic and mitotic chromosomes. During each division, relocates to the midbody microtubules.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily
Database Links

KEGG: dme:Dmel_CG6620

STRING: 7227.FBpp0079769

UniGene: Dm.3103

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1