Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) B3GNT2 Polyclonal antibody

Uniprot No.

Q9Z222

Target Names

B3GNT2

Alternative Names

B3GNT2 antibody; B3gnt1 antibody; Beta3gntN-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 antibody; EC 2.4.1.149 antibody; Beta-1,3-N-acetylglucosaminyltransferase 1 antibody; BGnT-1 antibody; Beta-1,3-Gn-T1 antibody; Beta3Gn-T1 antibody; Beta-1,3-galactosyltransferase 7 antibody; Beta-1,3-GalTase 7 antibody; Beta3Gal-T7 antibody; Beta3GalT7 antibody; b3Gal-T7 antibody; Beta-3-Gx-T7 antibody; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 antibody; BGnT-2 antibody; Beta-1,3-Gn-T2 antibody; Beta-1,3-N-acetylglucosaminyltransferase 2 antibody; Beta3Gn-T2 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7 antibody

Raised in

Rabbit

Species Reactivity

Mus musculus (Mouse)

Immunogen

Recombinant Mus musculus (Mouse) B3GNT2 protein

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Probably constitutes the main polylactosamine synthase.

Gene References into Functions

These data clearly suggest that GCNT2 functions in vivo together with beta3GnT2 to determine poly-N-acetyllactosamine (PLN) levels in olfactory neurons by regulating beta1,6-branches that promote PLN extension. PMID: 24105809
These results identify a novel function for beta3GnT2 glycosylation in maintaining expression of layer-specific vomeronasal receptors PMID: 23006775
Beta3GnT2(-/-) mice exhibit a relatively small deficit in their ability to discriminate divergent odors. PMID: 22559903
The results suggested taht beta3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium. PMID: 21525298
In beta1,3-N-acetylglucosaminyltransferase (B3gnt2) B3gnt2-deficient (B3gnt2-/-) mice, the number of polylactosamine structures was markedly lower than in wild-type mice PMID: 20816167
up-regulation of beta3Gn-T8 in differentiated cells increases poly-N-acetyllactosamine chains by activating intrinsic beta3Gn-T2. PMID: 18826941

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Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

Protein Families

Glycosyltransferase 31 family

Tissue Specificity

Expressed in heart, brain, lung, kidney and testis and, to a lesser extent, in liver and skeletal muscle. No expression in spleen.

Database Links

KEGG: mmu:53625

STRING: 10090.ENSMUSP00000053528

UniGene: Mm.395495

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B3GNT2 Antibody

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