CAND1 Antibody

Code CSB-PA817150XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CAND1 Polyclonal antibody
Uniprot No.
Target Names
CAND1
Alternative Names
CAND1 antibody; ETA2 antibody; HVE antibody; At2g02560 antibody; T8K22.14Cullin-associated NEDD8-dissociated protein 1 antibody; Cullin-associated and neddylation-dissociated protein 1 antibody; AtCAND1 antibody; Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 2 antibody; Protein HEMIVENATA antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CAND1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. Required for SCF(TIR1) function. Modulates SCF(TIR1) function through its interactions with the CUL1 subunit. Represses photomorphogenesis by promoting HY5 degradation in darkness.
Gene References into Functions
  1. HVE/CAND1 gene acts upstream of ATHB-8 at least in higher order veins, in a pathway that involves AXR1, but not LOP1, PIN1, CVP1 or CVP2. PMID: 16943276
  2. The disruption of the CAND1-CUL1 interaction results in an increased abundance of assembled SCF(TIR1) complex; stabilization of the CAND1-CUL1 interaction diminishes SCF(TIR1) complex abundance. PMID: 18550827
Protein Families
CAND family
Tissue Specificity
Highly expressed in roots. Expressed in stems, flowers and siliques.
Database Links

KEGG: ath:AT2G02560

STRING: 3702.AT2G02560.1

UniGene: At.41482

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