CCR4-4 Antibody

Code CSB-PA428858XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CCR4-4 Polyclonal antibody
Uniprot No.
Target Names
CCR4-4
Alternative Names
CCR4-4 antibody; HESP antibody; At1g31500 antibody; F27M3_27 antibody; T8E3.7 antibody; Carbon catabolite repressor protein 4 homolog 4 antibody; CCR4 homolog 4 antibody; EC 3.1.13.4 antibody; Protein HESPERIN antibody; AtHESP antibody; AtHesperin antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CCR4-4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Transcriptional regulator of circadian rhythms with poly(A)-degrading activity that affects the expression and rhythmicity of the clock core oscillator genes TOC1 and CCA1. Deadenylation may be a mechanism involved in the regulation of the circadian clock. May play a negative role in response against oxidative stress. Possesses magnesium-dependent poly(A)-specific exoribonuclease activity in vitro and is almost inactitve with poly(U), poly(C) and poly(G) as substrates.
Gene References into Functions
  1. Data show HESP as a novel transcriptional regulator of circadian rhythms with poly(A)-degrading activity that affects rhythmically expressed mRNAs while a negative role in the plant response against oxidative stress is also evident. [AtHESP] PMID: 26619288
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
CCR4/nocturin family
Database Links

KEGG: ath:AT1G31500

STRING: 3702.AT1G31500.4

UniGene: At.40328

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