slbo Antibody

Code CSB-PA997048XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) slbo Polyclonal antibody
Uniprot No.
Target Names
slbo
Alternative Names
slbo antibody; CG4354CCAAT/enhancer-binding protein antibody; C/EBP antibody; Slow border cell protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) slbo protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for the expression of gene products mediating border cell migration. Among the DNA sequences that this protein binds with high affinity is a conserved site within the promoter of its gene.
Gene References into Functions
  1. downregulated in delaminating epithelia as expression of Slbo is upregulated; this expression pattern during cell migration is achieved by negative feedback - slbo represses Trbl expression and trbl is necessary and sufficient to promote Slbo protein turnover PMID: 23305818
  2. Opposing interactions between Drosophila cut and the C/EBP encoded by slow border cells direct apical constriction and epithelial invagination PMID: 20450903
  3. The slbo protein, a C/EBP family transcriptional activator, is required for Border cells to become migratory. PMID: 16580994
Subcellular Location
Nucleus.
Protein Families
BZIP family, C/EBP subfamily
Database Links

KEGG: dme:Dmel_CG4354

STRING: 7227.FBpp0072179

UniGene: Dm.2680

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