AANAT1 Antibody

Datasheet

Code	CSB-PA959674XA01DLU
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) AANAT1 Polyclonal antibody

Uniprot No.

Q94521

Target Names

AANAT1

Alternative Names

AANAT1 antibody; Dat antibody; NAT1 antibody; CG3318Dopamine N-acetyltransferase antibody; EC 2.3.1.87 antibody; Arylalkylamine N-acetyltransferase antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) AANAT1 protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. In astrocytes, regulates sleep homeostasis by limiting the accumulation of serotonin and dopamine in the brain upon sleep deprivation. Is not essential for sclerotization.

Gene References into Functions

Data suggest Glu47 acts as general base with apparent pKa of 7.0 in biocatalysis by AANAT; 2 equally active variants exist, with AANATA differing from AANATB by truncation of 35 amino acids from N-terminus. [AANAT; arylalkylamine Nacetyltransferase] PMID: 25406072
Here we report a Drosophila dopamine-related locomotor endophenotype that is shared by pan-neuronal knockdown of orthologs of the ADHD-associated genes Dopamine transporter (DAT1) and Latrophilin (LPHN3), and of a gene causing a monogenic disorder with frequent ADHD comorbidity. PMID: 25962619
Dat is entirely responsible for a pigmentation difference between Drosophila species. PMID: 25769982
Dat possesses a specialized active site structure dedicated to a catalytic mechanism. PMID: 22716280
Dopamine-dependent arylalkylamine N-acetyltransferase plays a role in the regulation of dopamine content carried out by gonadotropins. PMID: 18038140

Hide All

Subcellular Location

Cytoplasm. Nucleus.

Tissue Specificity

In the adult, expressed in the midgut portion of the thoracic segments and the frontal half of the abdomen (at protein level). Expressed in the epithelial cell layer facing the lumen of the gut (at protein level). In the brain, expressed in a sub-populati

Database Links

KEGG: dme:Dmel_CG3318

STRING: 7227.FBpp0089101

UniGene: Dm.11356

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：