Doa Antibody

1. Doa could modulate pheromone production and sex behavior by altering sexual differentiation in the cuticle and the nervous system PMID: 28088352
2. Strong female-to-male sex transformations in double mutants of the IMD pathway in combination with Doa alleles, is reported. PMID: 26434917
3. DOA protein and its substrate EF-1gamma regulate organelle transport along microtubules. PMID: 24163433
4. LAMMER/Cdc2-like kinase, represented by Doa and its mammalian homolog CLK2, is a critical and conserved component in the regulatory program of the mitosis-to-meiosis switch PMID: 23376537
5. The Doa locus encodes six different kinases, of which a 69-kDa isoform is expressed solely in females. PMID: 20876993
6. DNA mutational analysis was done on Doa - a gene required for oocyte specification and development. PMID: 12930750
7. Data indicate that genes encoding proteins involved in closely related pathways are concentrated at certain loci to achieve more efficient regulation of their expression as exemplified from distribution of DOA protein on Drosophila polythene chromosomes. PMID: 16964964
8. DX16 could be a novel serine-arginine-rich protein phosphorylated by DOA and it may participate in the formation of splicing complex through its interactions with other splicing related proteins. PMID: 17828581
9. Alternative promoter usage generates multiple evolutionarily conserved isoforms of Drosophila DOA kinase. PMID: 18327787
10. the roles of the multiple isoforms, we mapped polymorphisms, deletions, and P-element insertions in the locus, identifying several that are largely, if not completely, isoform specific in their effects PMID: 18660538
11. mutations in the gene protect against the decrease in life span caused by the reactive oxygen species generator paraquat, associated with an increase in cytoplasmic and mitochondrial superoxide dismutase protein levels and activity PMID: 19135146

Show More

Hide All

KEGG: dme:Dmel_CG42320

STRING: 7227.FBpp0289029

UniGene: Dm.6767