Dyrk2 Antibody

Code CSB-PA895090XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Dyrk2 Polyclonal antibody
Uniprot No.
Target Names
Dyrk2
Alternative Names
Dyrk2 antibody; smi35A antibody; CG4551Dual specificity tyrosine-phosphorylation-regulated kinase 2 antibody; EC 2.7.12.1 antibody; Protein smell impaired at 35A antibody; dDyrk2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Dyrk2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
In vitro; can phosphorylate exogenous substrates on Ser and Thr residues. May have a physiological role in development being involved in cellular growth and differentiation.
Gene References into Functions
  1. DmDyrk2 is expressed in developing sensory systems and it is required for the development of the visual system. PMID: 24146926
  2. DYRK2 is an 81 kDa dual-specificity kinase that autophosphorylates on tyrosine and serine-threonine residues, but appears to phosphorylate exogenous substrates only on serine-threonine residues. PMID: 12786602
  3. This is the first instance of phosphorylation of SNR1 or any of its homologues and implicates the DYRK family of kinases with a role in chromatin remodelling. PMID: 16671894
Subcellular Location
Cytoplasm.
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily
Database Links

KEGG: dme:Dmel_CG4551

STRING: 7227.FBpp0302965

UniGene: Dm.2597

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