Fur2 Antibody

Code CSB-PA333527XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Fur2 Polyclonal antibody
Uniprot No.
Target Names
Fur2
Alternative Names
Fur2 antibody; CG18734Furin-like protease 2 antibody; Furin-2 antibody; EC 3.4.21.75 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Fur2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Gene References into Functions
  1. Study demonstrates that Furin proteases are required for Trk cleavage, and show that the Furin 1 and Furin 2 proteases act redundantly in terminal patterning in the Drosophila embryo. PMID: 26508274
  2. furin-cleavage sites in BMP2/4/DPP precursors are tolerant to mutations acquired through evolution and have adapted to different systems in diversified species PMID: 19433798
Subcellular Location
Membrane; Single-pass membrane protein.
Protein Families
Peptidase S8 family, Furin subfamily
Tissue Specificity
Transient expression in a subset of central nervous system neurons during embryonic stages 12-13. Expression in developing tracheal tree from stage 13 to end of embryonic development.
Database Links

KEGG: dme:Dmel_CG18734

STRING: 7227.FBpp0074038

UniGene: Dm.6383

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