Code | CSB-PA324949ZA01VAA |
Size | US$299 |
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To create the L1R antibody, a rabbit is immunized with recombinant vaccinia virus L1R (2-183aa), inducing the rabbit's B lymphocytes to produce specific IgG antibodies. The polyclonal L1R antibody is then meticulously purified from the rabbit's serum using protein G techniques. The functionality of this L1R antibody has been validated in both ELISA and WB tests. This L1R antibody can react with the vaccinia virus L1R protein.
L1R, a myristylated late gene product of the vaccinia virus, plays an essential role in the formation of infectious intracellular mature virions (IMV). The L1R gene-encoding protein L1 is located on the surface of IMVs and beneath the envelope of the extracellular enveloped virus (EEV). L1 is also involved in infection, as it has been observed that antibodies targeting L1 can effectively hinder the virus's invasion of host cells in its IMV form.
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