ptp-3 Antibody

Code CSB-PA858389XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ptp-3 Polyclonal antibody
Uniprot No.
Target Names
ptp-3
Alternative Names
ptp-3 antibody; C09D8.1/C09D8.2 antibody; Tyrosine-protein phosphatase Lar-like antibody; EC 3.1.3.48 antibody; Protein-tyrosine phosphate 3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ptp-3 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Has a role in early neural and epidermal development; neuroblast movements during closure of the gastrulation cleft and epidermal morphogenesis. Vab-1 and ptp-3 may function redundantly within the same sets of neuronal precursors.
Gene References into Functions
  1. These data are suggestive of ptp-3 as a potential negative regulator of several kinase families, such as the mitogen activated kinases (MAPKs), and multiple tyrosine kinases including FER, MET, and NTRK2. PMID: 27067626
  2. Long isoform PTP-3A acts as a molecular link between the extracellular matrix and alpha-liprin during synaptogenesis; the short isoform PTP-3B is extrasynaptic. PMID: 16107639
Subcellular Location
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein.
Protein Families
Protein-tyrosine phosphatase family, Receptor class 2A subfamily
Tissue Specificity
Both isoforms are ubiquitously expressed in early embryos. In later embryos, larvae and adults expression is highest in the nerve ring, dorsal cord, ventral cord and epithelial tissues.
Database Links

STRING: 6239.C09D8.1d

UniGene: Cel.5177

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