syd-2 Antibody

Datasheet

Code	CSB-PA637407XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans syd-2 Polyclonal antibody

Uniprot No.

Q21049

Target Names

syd-2

Alternative Names

syd-2 antibody; F59F5.6Liprin-alpha antibody; LAR-interacting protein alpha antibody; Synapse defective protein 2 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans syd-2 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1.

Gene References into Functions

N-terminal CC domains are responsible for the synaptogenic activity of SYD-2. PMID: 23541703
A main role of SYD-2/Liprin-alpha in synaptogenesis is to regulate the polymerization of DPs. PMID: 24322429
tudy shows that SYD-2 promotes bi-directional mobility of DCVs and identifies SYD-2 as a novel regulator of DCV trafficking and polarized distribution PMID: 23358451
Loss of function in C. elegans syd-2 Liprin-alpha alters the size of presynaptic specializations and disrupts synaptic vesicle accumulationA missense mutation in the coiled-coil domain of SYD-2 causes a gain of function. PMID: 17115037
SYD-2, SYD-1 and UNC-10 were found essential for presynaptic site active zone assembly at synapses PMID: 19436057

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Subcellular Location

Cell junction, synapse. Note=Presynaptic region.

Protein Families

Liprin family, Liprin-alpha subfamily

Tissue Specificity

Detected in vulval muscle and other cells near the vulva; in neurons located in the lateral ganglion, posterior ganglion, ventral cord and lateral body; and in pharyngeal and body wall muscle cells.

Database Links

KEGG: cel:CELE_F59F5.6

STRING: 6239.F59F5.6

UniGene: Cel.19549

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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syd-2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background