MAIL1 Antibody

Code CSB-PA572746XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MAIL1 Polyclonal antibody
Uniprot No.
Target Names
MAIL1
Alternative Names
MAIL1 antibody; At2g25010 antibody; Protein MAIN-LIKE 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MAIL1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts as an important factor for cell fate determination and maintenance throughout plant development. Required for the organization of the root apical meristem (RAM) and the shoot apical meristem (SAM). Required to maintain genome stability and cell division activity in meristematic cells.
Gene References into Functions
  1. Arabidopsis genes MAIL1 and MAIN define an alternative silencing pathway independent of DNA methylation and siRNAs. Mutants for MAIL1 or MAIN exhibit release of silencing and appear to show impaired condensation of pericentromeric heterochromatin. PMID: 28466841
  2. MAIL1 is essential for specification of cell fate in the primary root but not in anchor roots.[MAIL1] PMID: 25482792
  3. MAIN and MAIL1 act in the same pathway, and that both are essential for maintaining correct cell division acitivity in meristematic cells, while MAIL1 has an additional function in differentiating cells. PMID: 24635680
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in root tips, the shoot apical meristem (SAM), leaves, mature flowers and embryos.
Database Links

KEGG: ath:AT2G25010

UniGene: At.39075

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