MKP1 Antibody

Datasheet

Code	CSB-PA903524XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MKP1 Polyclonal antibody

Uniprot No.

Q9C5S1

Target Names

MKP1

Alternative Names

MKP1 antibody; At3g55270 antibody; T26I12.150 antibody; Protein-tyrosine-phosphatase MKP1 antibody; EC 3.1.3.48 antibody; Mitogen-activated protein kinase phosphatase 1 antibody; AtMKP1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana MKP1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Protein-tyrosine-phosphatase that acts as a negative regulator of MPK6 and MPK3 signaling by dephosphorylating and repressing MPK6 and MPK3. Modulates defense response by repressing salicylic acid (SA) production, camalexin biosynthesis and SNC1-mediated responses. Acts as a negative regulator of MPK6-mediated pathogen-associated molecular pattern (PAMP) responses, including MPK6 and MPK3 activation, accumulation of extracellular reactive oxygen species and inhibition of seedling growth. Involved in UV-B stress tolerance. May be involved in salt and genotoxic stress responses.

Gene References into Functions

These results provide insight into the roles of phosphorylation in the regulation of MKP1 during pathogen-associated molecular pattern signaling and resistance to bacteria. PMID: 29070514
MKP1 role in ultraviolet induced stomatal closure PMID: 27837091
These results identify MKP1 as a protein dually targeted to cytosol and peroxisomes. PMID: 25817413
mkp1, a mutant that is more resistant to bacterial infection, induces decreased levels of type III secretion system effectors in Pseudomonas syringae. PMID: 24753604
ATR and MKP1 play distinct roles in response to UV-B stress.MKP1-regulated and ATR-mediated DNA damage pathways operate independently of each other. PMID: 23237049
MKP1 is a phosphoprotein in vivo that MKP1 accumulates in response to UV-B stress PMID: 23188831
Regulation of MAPK phosphatase 1 (AtMKP1) by calmodulin in Arabidopsis. PMID: 18579522

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Subcellular Location

Cytoplasm, cytosol.

Database Links

KEGG: ath:AT3G55270

STRING: 3702.AT3G55270.1

UniGene: At.21664

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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