mlaD Antibody

Code CSB-PA353745XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) mlaD Polyclonal antibody
Uniprot No.
Target Names
mlaD
Alternative Names
mlaD antibody; yrbD antibody; b3193 antibody; JW3160 antibody; Intermembrane phospholipid transport system binding protein MlaD antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) mlaD protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. MlaD functions in substrate binding with strong affinity for phospholipids and modulates ATP hydrolytic activity of the complex.
Gene References into Functions
  1. The authors further demonstrate that MlaD forms extremely stable hexamers within the complex, functions in substrate binding with strong affinity for phospholipids, and modulates ATP hydrolytic activity. In addition, MlaB plays critical roles in both the assembly and activity of the MlaFEDB ATP-binding cassette transporter. PMID: 27529189
Subcellular Location
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein Families
MlaD family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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