OGG1 Antibody

Datasheet

Code	CSB-PA727222XA01DOA
Size	US$299
Image	Western Blot Positive WB detected in Recombinant protein All lanes: OGG1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 27.4 kDa Observed band size: 29 kDa
The Latest Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) OGG1 Polyclonal antibody

Uniprot No.

Q9FNY7

Target Names

OGG1

Alternative Names

OGG1 antibody; At1g21710 antibody; F8K7.14 antibody; N-glycosylase/DNA lyase OGG1 [Includes: 8-oxoguanine DNA glycosylase 1 antibody; AtOGG1 antibody; EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase antibody; AP lyase antibody; EC 4.2.99.18)] antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana OGG1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Protein A/G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The OGG1 polyclonal antibody is produced by injecting recombinant Arabidopsis thaliana OGG1 protein into a rabbit, which triggers the production of antibodies that target this antigen. Antibody production is increased with a booster injection, and the OGG1 polyclonal antibodies are collected from the rabbit's serum and purified using protein A/G. The OGG1 antibody's ability to specifically recognize Arabidopsis thaliana OGG1 protein has been confirmed through extensive testing in ELISA and WB assays.

The main function of Arabidopsis thaliana OGG1 protein is to repair DNA damage caused by oxidative stress. OGG1 is an enzyme that specifically recognizes and removes 8-oxoguanine (8-oxoG), a common DNA lesion resulting from oxidative damage. By excising the damaged base, OGG1 initiates the base excision repair pathway, which restores the integrity of the DNA molecule. This repair process helps maintain genomic stability and prevents the accumulation of mutations in Arabidopsis thaliana.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Involved in repair of DNA damaged by oxidation by incising DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (Fapy) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

Gene References into Functions

Arabidopsis cells use both FPG and OGG1 to repair 8-oxoG in a pathway that requires ZDP and ARP in downstream steps. PMID: 24934622
Overexpression of OGG1 enhances seed longevity and abiotic stress tolerance. PMID: 22473985

Subcellular Location

Nucleus.

Protein Families

Type-1 OGG1 family

Tissue Specificity

Expressed in stems, roots, rosette and cauline leaves, flowers and seeds.

Database Links

KEGG: ath:AT1G21710

STRING: 3702.AT1G21710.1

UniGene: At.10191

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

DNA repair pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：