GLC7 Antibody

1. We deleted the novel intronic RNA structure within the GLC7 intron and showed that this region, rather than the intron itself, is responsible for the cell's ability to respond to salt stress. We also showed a direct association between the in cis presence of the intronic RNA and GLC7 expression PMID: 27194751
2. Replacement of the N terminus of eIF2gamma with the GLC7-binding domain from GAC1 or fusion of heterologous dimerization domains to eIF2gamma and GLC7, respectively, maintained eIF2alpha phosphorylation at basal levels PMID: 24706853
3. Glc7 is involved in transcription termination. PMID: 24413056
4. summary of current knowledge of how Glc7 function modulates processes in the cytoplasm and nucleus; Additionally, global Glc7 regulation is described [review] PMID: 20800758
5. Data show that the Ref2 mutation, which renders it unable to bind Glc7, displays a marked decrease in lithium efflux, which can be explained by the inability of these cells to fully induce the Na+-ATPase ENA1 gene and blockage of the calcineurin pathway. PMID: 20028335
6. Glc7 activity promotes recovery from replication fork stalling caused by dNTP depletion and that gamma H2A dephosphorylation is a critical Glc7 function in this process. PMID: 19884341
7. Bud14p physically interacts with the type-I phosphatase Glc7p, and localizes Glc7p to the bud cortex. PMID: 16107882
8. Phosphatase activity of Glc7 strongly suggest a common role of two proteins in regulating Glc7 nuclear localization and function. PMID: 17142459
9. Data show that downregulation of Glc7, or its dissociation from CPF in the absence of CPF subunits Ref2 or Swd2, results in snoRNA termination defects. PMID: 18342605
10. The catalytic subunit of the budding yeast protein phosphatase 1 (PP1) homolog, Glc7, regulates exit from the spindle checkpoint. PMID: 19592248

Show More

Hide All

KEGG: sce:YER133W

STRING: 4932.YER133W