rab-28 Antibody

Code CSB-PA289264XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans rab-28 Polyclonal antibody
Uniprot No.
Target Names
rab-28
Alternative Names
rab-28 antibody; Y11D7A.4 antibody; Ras-related protein Rab-28 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans rab-28 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
GTPase. Intraflagellar transport (IFT) cargo that undergoes bidirectional IFT along the ciliary axoneme when in active GTP-bound state in amphid and phasmid ciliated sensory neurons. Targeting and function as IFT cargo may depend on the BBSome, an IFT cargo adapter. Does not undergo IFT when in inactive GDP-bound state. May in turn play a role in cilium structure and/or function in ciliated sensory neurons.
Gene References into Functions
  1. our findings present a new approach for identifying ciliary proteins, and unveil RAB28, a GTPase most closely related to the BBS protein RABL4/IFT27, as an IFT-associated cargo with BBSome-dependent cell autonomous and non-autonomous functions at the ciliary base. PMID: 27930654
Subcellular Location
Cell projection, cilium membrane; Peripheral membrane protein. Perikaryon. Cytoplasm, cytoskeleton, cilium axoneme.
Protein Families
Small GTPase superfamily, Rab family
Tissue Specificity
Expressed in amphid and phasmid ciliated sensory neurons.
Database Links

KEGG: cel:CELE_Y11D7A.4

STRING: 6239.Y11D7A.4

UniGene: Cel.12152

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