rhy-1 Antibody

Datasheet

Code	CSB-PA248115XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans rhy-1 Polyclonal antibody

Uniprot No.

Q9XVW1

Target Names

rhy-1

Alternative Names

rhy-1 antibody; W07A12.7 antibody; Regulator of hypoxia-inducible factor 1 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans rhy-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Involved in the response to variation in environmental oxygen levels by inhibiting hif-1-mediated gene transcription in a vhl-1-independent manner. Plays a role in susceptibility to killing mediated by P.aeruginosa and by pore-forming toxins produced by B.thuringiensis. Probably by preventing hif-1 transcriptional activity, regulates behavioral responses, such as locomotion speed following acute reoxygenation. Plays a role in normal egg-laying probably by regulating spermatogenesis and in body morphogenesis.

Gene References into Functions

The Caenorhabditis elegans rhy-1 gene inhibits hif-1 activity in a negative feedback loop that does not include vhl-1. PMID: 16980385

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity

Expressed in intestine, some sensory neurons in the head, body wall muscles and socket cells.

Database Links

KEGG: cel:CELE_W07A12.7

STRING: 6239.W07A12.7

UniGene: Cel.14204

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Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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