ruvb-1 Antibody

Datasheet

Code	CSB-PA964190XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans ruvb-1 Polyclonal antibody

Uniprot No.

O17607

Target Names

ruvb-1

Alternative Names

ruvb-1 antibody; C27H6.2 antibody; RuvB-like 1 antibody; EC 3.6.4.12 antibody; Pontin antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans ruvb-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Possesses single-stranded DNA-stimulated ATPase and ATP dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription. May participate in several chromatin remodeling complexes that mediate the ATP-dependent exchange of histones and remodel chromatin by shifting nucleosomes. Involvement in these complexes is likely required for transcriptional activation of selected genes and DNA repair in response to DNA damage. Involved in the Ce-Tor signaling pathway whereby it is required for the accumulation and localization of box C/D snoRNP to nucleoli to regulate ribosomal maturation and thus protein synthesis. Antagonizes the transcriptional activity of transcription factor pha-4, to control postembryonic development and adult longevity. Has a role in pharyngeal development. Has a role in gonadal development.

Gene References into Functions

characterized one dominant suppressor and discovered the mutation alters a likely cis-regulatory region within pha-4 itself. A second suppressor defined a new locus, the predicted AAA+ helicase ruvb-1. PMID: 17720918

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

RuvB family

Tissue Specificity

Expressed in gonadal cells.

Database Links

KEGG: cel:CELE_C27H6.2

STRING: 6239.C27H6.2

UniGene: Cel.17270

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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