RyR Antibody

Code CSB-PA632585XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) RyR Polyclonal antibody
Uniprot No.
Target Names
RyR
Alternative Names
RyR antibody; dry antibody; Rya-r44F antibody; CG10844Ryanodine receptor antibody; Ryanodine receptor 44F antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) RyR protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Intracellular calcium channel that is required for proper muscle function during embryonic development and may be essential for excitation-contraction coupling in larval body wall muscles.
Gene References into Functions
  1. The 46 aa segment of the Drosophila RyR C-terminus confers sensitivity to diamide insecticides. PMID: 23806522
  2. Ryanodine receptors are an important mediator of immobilization by volatile anesthetics. PMID: 23254148
Subcellular Location
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Protein Families
Ryanodine receptor (TC 1.A.3.1) family
Tissue Specificity
During embryonic stages 9-10, expression is seen in mesoderm of all segments in progenitors of the cephalic and somatic muscles. Adults exhibit high expression in tubular 'jump' muscles of thorax and leg, and lower expression in the brain, ventral ganglio
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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