set-1 Antibody

Datasheet

Code	CSB-PA631511XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans set-1 Polyclonal antibody

Uniprot No.

Q22795

Target Names

set-1

Alternative Names

set-1 antibody; T26A5.7 antibody; Histone-lysine N-methyltransferase set-1 antibody; EC 2.1.1.361 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans set-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched on hermaphrodite X chromosomes and during mitosis. Involved in dosage compensation by repression of X-linked gene expression in hermaphrodites. Plays a role in growth and body fat regulation downstream of the TOR complex 2 pathway.

Gene References into Functions

study reports that JMJD-3.1 and the H3K4 methyltransferase Set1 complex cooperate to ensure invariant transdifferentiation (Td) of postmitotic Caenorhabditis elegans hindgut cells into motor neurons PMID: 25124442
H3K4 methylation in the germline is regulated by a combination of Set1/MLL component-dependent and -independent modes of epigenetic establishment and maintenance. PMID: 21455483

Subcellular Location

Nucleus. Chromosome.

Protein Families

Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, PR/SET subfamily

Tissue Specificity

In embryos, it is expressed ubiquitously. In late embryos, it is expressed in hypodermal seam cells. In L3 and L4 larvae and thereafter, it is expressed in vulval precursor cells. In adult males, it is also expressed in 6 unidentified posterior cells.

Database Links

KEGG: cel:CELE_T26A5.7

STRING: 6239.T26A5.7a.1

UniGene: Cel.7462

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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set-1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background