snf-6 Antibody

Datasheet

Code	CSB-PA524929XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans snf-6 Polyclonal antibody

Uniprot No.

O76689

Target Names

snf-6

Alternative Names

snf-6 antibody; M01G5.5Sodium-dependent acetylcholine transporter antibody; Sodium:neurotransmitter symporter family protein 6 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans snf-6 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-glycoprotein complex (DGC) function results in muscle degeneration.

Gene References into Functions

mutations result in phenotypes indistinguishable from those of the dystrophin-glycoprotein complex (DSC) mutants, and snf-6 encodes a novel acetylcholine/choline transporter PMID: 15318222

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=The DGC is not necessary to establish snf-6 at the postsynaptic membrane, but it is required for maintenance or stabilization.

Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Tissue Specificity

Body wall, and vulval and enteric muscles.

Database Links

KEGG: cel:CELE_M01G5.5

STRING: 6239.M01G5.5

UniGene: Cel.28751

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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snf-6 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background