sox2 Antibody

1. Findings indicate a pivotal role for ZNF32 function in SOX2 expression and regeneration regulation. PMID: 27626680
2. Both sox2 and p27kip are regulated by the retinoic acid signal pathway and are essential for hair cell regeneration. PMID: 26609166
3. a role of Sox2 as one of the proliferation initiators in ependymal cells after spinal cord injury PMID: 25150399
4. Sox2 is identified as the unknown factor responsible for pineal photoreceptor prepatterning and performs this function independently of the BMP signaling. PMID: 24498133
5. By western blot three protein bands of 28 kDa, 34 kDa (main band), and 38 kDa were detected in the brain of animals 180 days post-fertilizaton. PMID: 20734413
6. significant decreases in sox2 (up to 4-fold) expression following chilling and increase of sox2 (up to 3-fold) during warming of chilled embryos. PMID: 21820425
7. sox2 is required for hair cell survival, as well as for transdifferentiation of support cells into hair cells during regeneration PMID: 20025865
8. shows the occurrence and cell localization of the Sox-2 in chemosensory and mechanosensory organs of zebrafish during the embryonic stage to adult, suggest an involvement of Sox-2 in cell renewal of zebrafish sensory organs PMID: 19800392
9. zebrafish sox2 gene is strongly expressed in neuromast progenitor cells, including those of the migrating lateral line PMID: 17443814
10. Sox2 overlapping transcript has multiple transcription start sites associated with genomic features that indicate regulated expression, including highly conserved elements and chromatin marks characteristic of gene promoters. PMID: 19767420

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KEGG: dre:378723

STRING: 7955.ENSDARP00000095266

UniGene: Dr.5379