Syn Antibody

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Code	CSB-PA630514XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Syn Polyclonal antibody

Uniprot No.

Q24546

Target Names

Syn

Alternative Names

Syn antibody; Syn-1 antibody; Syn-2 antibody; CG3985 antibody; Synapsin [Cleaved into: Synapsin-1 antibody; Syn1 antibody; Syn1-S); Synapsin-2 antibody; Syn2)] antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Syn protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Plays a significant role in nervous system function, which is subtle at the cellular level but manifests itself in complex behavior.

Gene References into Functions

We show that after odor-high salt conditioning larvae form two parallel memory phases; a short lasting component that depends on cyclic adenosine 3'5'-monophosphate (cAMP) signaling and synapsin gene function PMID: 27768692
Synapsin is required for short- but not longer-term memory. PMID: 26670182
This study report Synapsin as a determinant for memory strength in a behavioral assay of timing-dependent associative plasticity. PMID: 25972175
This study demonistrated that support a model whereby synapsin accumulates at sites of synaptic growth and facilitates budding of new boutons via a cAMP/PKA-dependent pathway. PMID: 25100589
these data support a model in which CaMKII-mediated synapsin phosphorylation in local circuit interneurons induces synaptic vesicle mobilization and thereby presynaptic facilitation of GABA release that underlies olfactory short-term habituation. PMID: 24133261
This study synapsin acts in associative memory trace formation in the mushroom bodies, as a downstream element of AC-cAMP-PKA signaling. PMID: 21518740
these results elucidate a novel synapsin function, specifically, promoting vesicle reuptake and reserve pool formation upon intense stimulation. PMID: 20638447
larval Drosophila can be used as a case study for a role of Synapsin in associative learning PMID: 15930500
synapsin maintains the reserve pool of vesicles and segregation between the recycling and reserve pools PMID: 17904536

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Subcellular Location

Cell junction, synapse.

Protein Families

Synapsin family

Tissue Specificity

Widely expressed in the embryonic and adult nervous system synaptic terminals.

Database Links

KEGG: dme:Dmel_CG3985

STRING: 7227.FBpp0099901

UniGene: Dm.6815

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Syn Antibody

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