TIP1-1 Antibody

Code CSB-PA328569XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TIP1-1 Polyclonal antibody
Uniprot No.
Target Names
TIP1-1
Alternative Names
TIP1-1; AQP.1; At2g36830; T1J8.1; Aquaporin TIP1-1; Aquaporin TIP; Gamma-tonoplast intrinsic protein; Gamma-TIP; Tonoplast intrinsic protein 1-1; AtTIP1;1; Tonoplast intrinsic protein, root-specific RB7
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana TIP1-1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Water channel required to facilitate the transport of water, diffusion of amino acids and/or peptides from the vacuolar compartment to the cytoplasm. Does not promote glycerol permeability. May play a role in the control of cell turgor and cell expansion. Its function is impaired by Hg(2+). May be involved in a vesicle-based metabolite routing through or between pre-vacuolar compartments and the central vacuole. Transports urea in yeast cells in a pH-independent manner. Transports H(2)O(2) in yeast cells.
Gene References into Functions
  1. Data show that the highly abundant tonoplast aquaporins (AQPs) isoforms AtTIP1;1, AtTIP1;2, and AtTIP2;1 facilitate the emergence of new lateral root primordia (LRPs). PMID: 26802038
  2. TIP1;1 and TIP1;2 single or double mutants did not show significant changes in water content or water retention, and showed no sign of early senescence or growth retardation. [TIP1;1] PMID: 18643996
  3. unlike for TIP1;1, trafficking of markers for TIP3;1 and TIP2;1 is insensitive to Brefeldin A in Arabidopsis hypocotyls PMID: 22957103
  4. AtTIP1;1 is present in multiple vacuolar compartments and is preferentially found in the apposing tonoplasts of adjacent vacuoles. AtTIP1;1 loss of function did not lead to early plant death. PMID: 19229639
Subcellular Location
Vacuole membrane; Multi-pass membrane protein.
Protein Families
MIP/aquaporin (TC 1.A.8) family, TIP (TC 1.A.8.10) subfamily
Tissue Specificity
In all the vegetative organs, but not in seeds. Preferentially expressed in roots.
Database Links

KEGG: ath:AT2G36830

STRING: 3702.AT2G36830.1

UniGene: At.25221

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