TOM20 Antibody

1. Pex3p was targeted to mitochondria by fusion with the mitochondrial targeting signal of Tom20p. PMID: 20655617
2. Tom20 has a dual role in protein import into mitochondria: recognition of the targeting signal in the presequence and tethering the presequence to the TOM40 complex to increase import efficiency. PMID: 21173275
3. Our data reveal a large-scale mRNA association mode that involves interaction of Tom20p with the translated mitochondrial targeting sequence and may be assisted by Puf3p. PMID: 19858288
4. Data Show that Tom20 are anchored in the outer membrane by a single transmembrane alpha-helix, located at the N terminus of Tom20 (signal-anchored) and that Mim1 is required for efficient membrane insertion and assembly of Tom20. PMID: 17974559
5. Tom20 and Tom22 are apparently involved in the same step or sequential steps along the same pathway of targeting signal recognition in import PMID: 18063580
6. These data show that the homo-oligomerization of Mim1 allows it to fulfil its function in promoting the integration of Tom20 into the mitochondrial outer membrane. PMID: 18177669
7. Study shows that the transmembrane segment of Tom20 contains critical residues essential for docking the Tom20 receptor into its correct environment within the TOM complex; the docking reaction is catalyzed by the unique assembly factor Mim1/Tom13. PMID: 18187149

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KEGG: sce:YGR082W

STRING: 4932.YGR082W