UVR3 Antibody

Code CSB-PA526168XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UVR3 Polyclonal antibody
Uniprot No.
Target Names
UVR3
Alternative Names
UVR3 antibody; At3g15620 antibody; SJ11.2 antibody; (6-4)DNA photolyase antibody; EC 4.1.99.13 antibody; Protein UV repair defective 3 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana UVR3 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in repair of UV radiation-induced DNA damage. Catalyzes the photoreactivation of pyrimidine [6-4] pyrimidone photoproduct (6-4 products). Binds specifically to DNA containing 6-4 products and repairs these lesions in a visible light-dependent manner. Not required for repair of cyclobutane pyrimidine dimer (CPD).
Gene References into Functions
  1. Data show that mitochondrial and chloroplast localization of DNA photolyase AtUVR3 (UVR3) is independent of its N-terminal sequence. PMID: 29069446
  2. In darkness, expression of the PHR1 and UVR3 photolyase genes, responsible for photoreactivation, is maintained at a basal level through the positive action of HY5 and HYH photomorphogenesis-promoting transcription factors PMID: 20487384
  3. the key step in the repair photocycle is acyclic proton transfer between the enzyme and the substrate PMID: 20657578
  4. regulation of FAD redox properties and radical stability is essential not only for (6-4) photoproduct DNA repair, but also for circadian clock-regulating CRY functions PMID: 19359474
Protein Families
DNA photolyase class-1 family
Tissue Specificity
Expressed in siliques, flowers and leaves. Not detected in roots.
Database Links

KEGG: ath:AT3G15620

STRING: 3702.AT3G15620.1

UniGene: At.188

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