wgn Antibody

Datasheet

Code	CSB-PA933095XA01DLU
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) wgn Polyclonal antibody

Uniprot No.

Q9VWS4

Target Names

wgn

Alternative Names

wgn antibody; Vader antibody; CG6531Tumor necrosis factor receptor superfamily member wengen antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) wgn protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Receptor for egr. Involved in induction of apoptosis by triggering JNK signaling. Mediates the tumor suppressor activity of egr which eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity. Following UV-induced epidermal damage, binds to egr released from apoptotic epidermal cells and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious. Together with Moe, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr.

Gene References into Functions

roles of wengen PMID: 21153308
results suggest that Wengen can act as a component of a functional receptor for Eiger PMID: 12084706
Eiger and Wengen represent proximal components of an evolutionarily conserved TNF-like signaling pathway in Drosophila. PMID: 12894227

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

In third instar larvae, detected in photoreceptor neurons, including R8 photoreceptors, and also in adult head (at protein level). Expression appears to be very low or undetectable in pregastrulating embryos. During gastrulation, detected in the inner lay

Database Links

KEGG: dme:Dmel_CG6531

STRING: 7227.FBpp0074388

UniGene: Dm.13466

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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