Specifically designed for canine species, the Canine Creatine Kinase MB isoenzyme (CK-MB) ELISA kit is optimized for the quantitative detection of CK-MB in serum and plasma samples. This kit offers a detection range from 1.56 μIU/mL to 100 μIU/mL with a sensitivity of 31.25 ng/mL, providing precise measurements based on a competitive assay principle. It usually takes 1 to 5 hours to complete the detection and needs about 50-100 μl sample.
Canine Creatine Kinase MB isoenzyme (CK-MB) is a specific form of creatine kinase found in dogs. It is a valuable biomarker for assessing myocardial damage in canines. Studies have focused on evaluating CK-MB levels in various conditions, such as chronic mitral valve disease and visceral leishmaniasis. Dogs with cardiovascular diseases exhibit significantly higher CK-MB levels compared to healthy subjects [1][2]. Furthermore, CK-MB is used alongside other cardiac markers, such as cardiac troponins, to assess cardiac injury in dogs.
References:
[1] U. Bakirel and S. Güneş, "Value of cardiac markers in dogs with chronic mitral valve disease", Acta Veterinaria, vol. 59, no. 2-3, p. 223-229, 2009. https://doi.org/10.2298/avb0903223b
[2] V. Silva, M. Sousa, C. Araujo, A. Lima, & R. Carareto, "Cardiac biomarkers in dogs with visceral leishmaniasis", Archivos De Medicina Veterinaria, vol. 48, no. 3, p. 269-275, 2016. https://doi.org/10.4067/s0301-732x2016000300004
