Code | CSB-EL006241MO |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * Sample kit cost can be deducted as a $30 credit for each 96-assay kit of the same analyte and brand you subsequently purchase in six months till depleted. Apply now |
The product CSB-EL006241MO is a sandwich ELISA kit developed to measure concentrations of mouse CXCL11 in serum, plasma, cell culture supernates, or tissue homogenates. This assay uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of CXCL11 in samples. The color intensity is measured at 450 nm via a microplate reader.
CXCL11, also known as I-TAC, mainly functions as an inflammatory chemokine that recruits T cells, NK cells, and monocytes/macrophages at sites of infection, predominantly through the receptor CXCR3. CXCL11 can mediate inflammatory responses, leukocyte trafficking, adaptive resistance, hematopoiesis, cancer cell transfer, and angiogenesis. CXCL11 signals through CXCL11, stimulating numerous downstream signaling pathways which are involved in tumorigenicity, growth, apoptosis, angiogenesis, invasion, and metastasis of cancer cells. CXCL11 has also been reported to be associated with a poor response to therapy.
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