LANCL1 Antibody

Datasheet

Code	CSB-PA012742LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse heart tissue, Mouse liver tissue, Mouse stomach tissue All lanes: LANCL1 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012742LA01HU at dilution of 1:100 Immunofluorescent analysis of U251 cells using CSB-PA012742LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LANCL1 Polyclonal antibody

Uniprot No.

O43813

Target Names

LANCL1

Alternative Names

40 kDa erythrocyte membrane protein antibody; G protein-coupled receptor 69A antibody; GPR69A antibody; LanC (bacterial lantibiotic synthetase component C) like 1 antibody; LanC lantibiotic synthetase component C like 1 (bacterial) antibody; LanC-like protein 1 antibody; LANC1_HUMAN antibody; LANCL1 antibody; p40 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human LanC-like protein 1 protein (50-150AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LANCL1 Antibody (Product code: CSB-PA012742LA01HU) is Non-conjugated. For LANCL1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA012742LB01HU	LANCL1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012742LC01HU	LANCL1 Antibody, FITC conjugated
Biotin	CSB-PA012742LD01HU	LANCL1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione.

Gene References into Functions

Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense. PMID: 22891245
the crystal structures of human LanCL1, both free of and complexed with glutathione, revealing glutathione binding to a zinc ion at the putative active site formed by conserved GxxG motifs PMID: 19528316

Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein.

Protein Families

LanC-like protein family

Tissue Specificity

Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.

Database Links

HGNC: 6508

OMIM: 604155

KEGG: hsa:10314

STRING: 9606.ENSP00000233714

UniGene: Hs.13351

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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