Recombinant Human Kallikrein-9 (KLK9)

Code CSB-YP892334HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP892334HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP892334HU
MSDS
Size Pls inquire
Source Baculovirus
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
KLK9
Uniprot No.
Alternative Names
KLK9Kallikrein-9; EC 3.4.21.-; Kallikrein-like protein 3; KLK-L3
Species
Homo sapiens (Human)
Expression Region
16-250
Target Protein Sequence
HGWAD TRAIGAEECR PNSQPWQAGL FHLTRLFCGA TLISDRWLLT AAHCRKPYLW VRLGEHHLWK WEGPEQLFRV TDFFPHPGFN KDLSANDHND DIMLIRLPRQ ARLSPAVQPL NLSQTCVSPG MQCLISGWGA VSSPKALFPV TLQCANISIL ENKLCHWAYP GHISDSMLCA GLWEGGRGSC QGDSGGPLVC NGTLAGVVSG GAEPCSRPRR PAVYTSVCHY LDWIQEIMEN
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. Pronounced correlations between KLK10/KLK11 (rs = 0.647) and between KLK9/KLK15 (rs = 0.716) mRNA, but not between other combinations, indicate coordinate expression of distinct pairs of peptidases PMID: 29095848
  2. Data suggest that mature KLK9 (kallikrein 9) is a glycosylated chymotrypsin-like enzyme with strong preference for tyrosine over phenylalanine at P1 cleavage position; substrate specificity of KLK9 appears to extend to KLK10 and midkine; enzyme activity is enhanced by Mg2+ and Ca2+, but is reversibly attenuated by Zn2+; KLK9 is inhibited in vitro by many naturally occurring or synthetic protease inhibitors. PMID: 28559305
  3. Data demonstrate that elevated levels of KLK6, KLK7 and KLK9 proteins are associated with poor glioblastoma patients survival. PMID: 26231762
  4. the serum level has the potential to be used as a biomarker for asthma PMID: 25747782
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20424135

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Subcellular Location
Secreted.
Protein Families
Peptidase S1 family, Kallikrein subfamily
Tissue Specificity
Skin, thymus, trachea, cerebellum and spinal cord.
Database Links

HGNC: 6370

OMIM: 605504

KEGG: hsa:284366

STRING: 9606.ENSP00000366028

UniGene: Hs.448942

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