Recombinant Human Paired mesoderm homeobox protein 2 (PRRX2)

Code CSB-YP859944HU
MSDS
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Source Yeast
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Code CSB-EP859944HU
MSDS
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Source E.coli
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Code CSB-EP859944HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP859944HU
MSDS
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Source Baculovirus
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Code CSB-MP859944HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PRRX2
Uniprot No.
Alternative Names
Paired mesoderm homeobox protein 2; Paired related homeobox protein 2 ; paired-like homeobox gene 2; paired-like homeodomain protein PRX2; Paired-related homeobox protein 2; PMX2 ; Predicted NUP98/PRRX2 fusion protein; Prrx2; PRRX2_HUMAN; PRX 2; PRX-2; PRX2
Species
Homo sapiens (Human)
Expression Region
1-253
Target Protein Sequence
MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
Gene References into Functions
  1. These data suggest that upregulation of PRRX2 may be a mechanism contributing to TGF-beta-induced invasion and epithelial mesenchymal transition in breast cancer. PMID: 26824226
  2. Encodes homeobox transcription factors that are expressed during vasculogenesis. PMID: 11893718
  3. Valsartan, a selective Ang II type 1 (AT1) receptor blocker, and N-acetylcysteine, an antioxidant, inhibited both of these modifications, indicating the contribution of AT1 receptor and reactive oxygen species to oxidation of Prx2. PMID: 17964282
Subcellular Location
Nucleus.
Protein Families
Paired homeobox family
Tissue Specificity
In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in d
Database Links

HGNC: 21338

OMIM: 604675

KEGG: hsa:51450

STRING: 9606.ENSP00000361547

UniGene: Hs.660115

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