Recombinant Human Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD)

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Code CSB-EP880077HU
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Size $224
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity
Greater than 90% as determined by SDS-PAGE.
Target Names
PISD
Uniprot No.
Alternative Names
DJ858B16; dJ858B16.2; DKFZp566G2246; Phosphatidylserine decarboxylase; Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase proenzyme; PISD; PISD_HUMAN; PSD; PSDC; PSSC
Species
Homo sapiens (Human)
Source
E.coli
Expression Region
1-375aa
Target Protein Sequence
MMCQSEARQGPELRAAKWLHFPQLALRRRLGQLSCMSRPALKLRSWPLTVLYYLLPFGALRPLSRVGWRPVSRVALYKSVPTRLLSRAWGRLNQVELPHWLRRPVYSLYIWTFGVNMKEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGRILNFGQVKNCEVEQVKGVTYSLESFLGPRMCTEDLPFPPAASCDSFKNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIYFDRDLHTNSPRHSKGSYNDFSFVTHTNREGVPMRKGEHLGEFNLGSTIVLIFEAPKDFNFQLKTGQKIRFGEALGSL
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
56.0kDa
Protein Length
Full Length of Isoform 2
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
Tris-based buffer,50% glycerol
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description

The Recombinant Human PISD is an essential research tool for scientists investigating the role of Phosphatidylserine decarboxylase proenzyme in metabolism. This mitochondrial protein plays a critical role in the biosynthesis of phosphatidylethanolamine, which is a vital component of cellular membranes and has implications in various cellular processes.

Our Recombinant Human PISD is the full length of Isoform 2 (1-375aa), ensuring an accurate representation for your research needs. Expressed in E. coli, this protein features an N-terminal 6xHis-SUMO tag for convenient purification and detection. With a purity greater than 90% as determined by SDS-PAGE and available in both liquid and lyophilized powder forms, this high-quality recombinant protein offers the reliability and performance necessary for your metabolism-focused research.

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Target Background

Function
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
Gene References into Functions
  1. High-throughput mass spectrometry screening for inhibitors of PISD is reported. PMID: 17478478
Subcellular Location
[Phosphatidylserine decarboxylase beta chain]: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.; [Phosphatidylserine decarboxylase alpha chain]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein Families
Phosphatidylserine decarboxylase family, PSD-B subfamily, Eukaryotic type I sub-subfamily
Database Links

HGNC: 8999

OMIM: 612770

KEGG: hsa:23761

STRING: 9606.ENSP00000266095

UniGene: Hs.420559

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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