Recombinant Rat Gastrin-releasing peptide (Grp)

1. These results suggest that androgen surge during male puberty plays an important role in the development and maintenance of the male-specific GRP function in the rat spinal cord. PMID: 26860455
2. feeding responses evoked by the large molecular form of gastrin releasing peptide (GRP) in the rat PMID: 24993846
3. all forms of GRP reduce food intake in obese and lean adult Zucker rats similar to Bn in weanling rats. PMID: 24874706
4. The site of action of rat gastrin releasing peptide, in regulation of meal size and intermeal interval, is most likely the stomach and/or the duodenum. PMID: 24556509
5. Gastrin-releasing peptide terminals were found in spinal dorsal horn and trigeminal ganglion. PMID: 24254931
6. GRP regulation of meal size and intermeal interval occurs at different sites in the rat. PMID: 24291388
7. Gastrin-releasing peptide acts via postsynaptic bombesin type 2 receptors to modulate inward rectifier K+ and TRPV1-like conductances in rat paraventricular thalamic neurons PMID: 23359674
8. reduction of meal size and prolongation of intermeal interval (IMI) by GRP-29 require vagal and splanchnic nerves, and the duodenum is the major conduit that communicates prolongation of IMI by GRP-29 with the brain PMID: 22210008
9. With increasing levels of fear, levels of gastrin-releasing peptide (Grp) are increased in medial prefrontal cortex and basolateral amygdala. PMID: 20974156
10. GRP-29 and GRP-27 reduced the size of the first meal, prolonged intermeal interval and increased satiety ratio, but GRP-10 failed to exhibit similar feeding responses. The data support a role for GRP-29 in the short-term regulation of food intake. PMID: 21055429
11. These high-voltage electron microscopy findings provide an ultrastructural basis for understanding how the spinal GRP system regulates male sexual behavior. PMID: 19864484
12. Data suggest that GRP, by acting on GRP receptors but not via CRF receptors, increases 5-HT neuronal activity in the paraventricular nucleus. PMID: 12138009
13. GRP in the central part of the amygdala inhibits feeding, may decrease the efficiency of eating, and may act as a satiety signal. PMID: 12419521
14. the increase in gastrin relesing peptide synthesis in the neurosecretory structures of the hypothalamus shoud be regarded as a compensatory reaction in diabetes PMID: 12469881
15. GRP mRNA was detected in rat kidney from embryonic day 19 to postnatal day 30 by RT-PCR PMID: 15140764
16. Data suggest that GRP does affect the stress response. GRP alterations selectively affected fear-related responses. PMID: 17335915
17. Food deprivation and stimulation of the melanocortin system produce opposing changes in GRP gene expression in the PVN; GRP-containing neurons in the PVN may be part of the hypothalamic signaling pathway controlling food intake and energy balance. PMID: 18818295
18. the spinal GRP system appears to be a stress-vulnerable center for male reproductive functions PMID: 19169356
19. Results suggest that androgen signaling plays a pivotal role in the regulation of GRP expression in male lumbar spinal cord. PMID: 19359382

Show More

Hide All

KEGG: rno:171101

STRING: 10116.ENSRNOP00000022845

UniGene: Rn.10930