Code | CSB-RA023441MA1HU |
Size | US$210 |
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The TFRC recombinant monoclonal antibody production generally commences with the insertion of the TFRC antibody-encoding gene into expression vectors. These vectors are subsequently delivered into host cells through polyethyleneimine-mediated transfection. The host cells, housing these vectors, are cultured to generate and release the antibodies. Following purification via affinity chromatography, the antibodies are subjected to assessments through ELISA, confirming their ability to recognize the human TFRC protein. In the functional ELISA, immobilized human TFRC protein (CSB-MP3648HU) at 2 μg/mL can bind this TFRC recombinant monoclonal antibody, with the EC50 of 3.305-8.220 ng/mL.
TFRC is a critical protein involved in the cellular uptake of iron, which is essential for various cellular processes and the maintenance of overall iron homeostasis in the body. Its function is pivotal for supporting the growth and normal functioning of cells and tissues.
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