BAFF (B-cell activating factor) is a cytokine produced by myeloid cells, belonging to the tumor necrosis factor family, which plays a crucial role in the survival, proliferation, antigen presentation, and class switch recombination of B cells. By binding to three receptors (TNFRSF13B/TACI, TNFRSF17/BCMA, TNFRSF13C/BAFFR), it activates multiple signaling pathways, including NF-κB, MAPK (mitogen-activated protein kinase), and PI3K/AKT, among others. These signaling pathways play significant roles in the biological processes of B cells and immune regulation. However, excessive production and activation of BAFF may also lead to the development of autoimmune diseases. Therefore, an in-depth study of the structural function of BAFF and the signaling pathways it participates in is of great significance for understanding its role in the immune system and developing treatment methods for related diseases.
The following BAFF reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BAFF Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA023990GA01HU | TNFSF13B Antibody |
Human | ELISA,WB |
CSB-PA05767A0Rb | TNFSF13B Antibody |
Human | ELISA |
CSB-PA897523ESR2HU | TNFSF13B Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA005018 | TNFSF13B Antibody |
Human,Mouse | WB, ELISA |
CSB-PA981923 | TNFSF13B Antibody |
Human | ELISA,WB,IHC |
CSB-PA108957 | TNFSF13B Antibody |
Human | ELISA,IHC |
BAFF Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP897523HU CSB-BP897523HU CSB-MP897523HU CSB-EP897523HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP897523HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B), partial |
E.coli |
CSB-AP002191HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) |
E.Coli |
CSB-MP897523HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) |
Mammalian cell |
CSB-MP897523HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial,Biotinylated (Active) |
Mammalian cell |
BAFF ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E11912h | Human B cell activation factor,BAFF ELISA Kit |
serum, plasma, tissue homogenates | 0.078 ng/mL |