CD163 is a cysteine-rich scavenger receptor type B encoded by the CD163 gene, which is primarily expressed in monocytes, macrophages, and macrophage cell lines. Its structure comprises an extracellular domain consisting of 1048 amino acid residues, a transmembrane segment, and a cytoplasmic tail. Although CD163 does not directly trigger typical signaling cascades like some receptors, it influences intracellular signaling by interacting with other molecules. As a scavenger receptor for hemoglobin-haptoglobin complexes, CD163 participates in the clearance of hemoglobin and iron recycling. Furthermore, it plays a crucial role in regulating immune responses, such as inhibiting the production of inflammatory factors and promoting the expression of anti-inflammatory factors, thereby exerting a significant impact in inflammatory diseases and tumors.
The following Cd163 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Cd163 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA969205 | CD163 Antibody |
Human | ELISA,IHC |
CSB-RA801238A0HU | CD163 Recombinant Monoclonal Antibody |
Human | ELISA, IHC, FC |
CSB-PA801238LA01HU | CD163 Antibody |
Human | ELISA, IF |
CSB-PA801238LB01HU | CD163 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA801238LC01HU | CD163 Antibody, FITC conjugated |
Human | |
CSB-PA801238LD01HU | CD163 Antibody, Biotin conjugated |
Human | ELISA |
CSB-MA942955 | CD163 Monoclonal Antibody |
Human | ELISA, IHC |
Cd163 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP801238HU CSB-BP801238HU CSB-MP801238HU CSB-EP801238HU-B |
Recombinant Human Scavenger receptor cysteine-rich type 1 protein M130 (CD163), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP801238HU | Recombinant Human Scavenger receptor cysteine-rich type 1 protein M130 (CD163), partial |
E.coli |
Cd163 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E14050h | Human soluble CD163(sCD163) ELISA Kit |
serum, plasma, tissue homogenates | 0.39 ng/mL |