The protein encoded by the FANCA gene is a crucial member of the Fanconi anemia complementation group (FANC), whose structure may involve multiple transcriptional variants of subtypes. Although the specific signaling pathways that FANCA directly participates in are not fully understood, it plays a vital role in DNA damage repair and maintaining genome stability. FANCA, along with other FANC proteins, is recruited to DNA damage sites to participate in the DNA repair process, thus preventing the occurrence of cellular mutations, cancer, and genetic diseases. Dysfunction or mutations in FANCA can lead to Fanconi anemia, a hereditary bone marrow failure syndrome. Therefore, the study of the FANCA gene and its encoded protein is significant for understanding and treating diseases such as Fanconi anemia.
The following FANCA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FANCA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008413GA01HU | FANCA Antibody |
Human | ELISA,WB,IHC |
CSB-PA008175 | Phospho-FANCA (S1149) Antibody |
Human | WB, IHC, IF, ELISA |
CSB-PA008176 | FANCA Antibody |
Human | IHC, ELISA |
CSB-PA008413LA01HU | FANCA Antibody |
Human | ELISA, IF |
CSB-PA008413LB01HU | FANCA Antibody, HRP conjugated |
Human | ELISA |
CSB-PA008413LC01HU | FANCA Antibody, FITC conjugated |
Human | |
CSB-PA008413LD01HU | FANCA Antibody, Biotin conjugated |
Human | ELISA |
FANCA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP008413HU CSB-EP008413HU CSB-BP008413HU CSB-MP008413HU CSB-EP008413HU-B |
Recombinant Human Fanconi anemia group A protein (FANCA), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |