HBD, or δ-pearson gene, is the gene that encodes the δ-chain in the haemoglobin HbA2, located on human chromosome 11.HbA2 is a tetrameric haemoglobin consisting of two α-chains and two δ-chains, and accounts for a small fraction of the total haemoglobin in adults, usually around 2-3%.The HBD gene is actively expressed during the foetal period, and, together with the γ-chain (encoded by the HBG1 and HBG2 genes) are involved in the formation of foetal haemoglobin HbF, which contributes to the transport of oxygen from the mother to the foetus in utero. In adulthood, the expression of the HBD gene decreases and the adult haemoglobin HbA (encoded by the HBA1 and HBB genes) becomes the predominant form.Mutations or aberrant expression of the HBD gene have been associated with certain types of thalassaemia, an inherited disease that affects the synthesis and function of haemoglobin. Thus, HBD is biologically important in foetal development, oxygen transport and the development of related blood disorders.
● Recombinant Human Hemoglobin subunit delta (HBD)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA010152LA01HU at dilution of 1:100
The following HBD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HBD Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010152GA01HU | HBD Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA010152LA01HU | HBD Antibody |
Human | ELISA, IHC |
HBD Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010152HU CSB-BP010152HU CSB-MP010152HU CSB-EP010152HU-B |
Recombinant Human Hemoglobin subunit delta (HBD) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP010152HU | Recombinant Human Hemoglobin subunit delta (HBD) |
E.coli |
HBD ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL010152HU | Human Hemoglobin subunit delta(HBD) ELISA kit |
serum, plasma, lysate for RBC. | 0.007 ng/mL |