HP, or Haptoglobin, is a plasma glycoprotein synthesised by the liver. It works by binding to haemoglobin, forming a stable complex that reduces haemoglobin breakdown in the blood vessels and prevents the toxic effects of iron ions and haemoglobin, while facilitating haemoglobin clearance and iron recycling.The mechanisms of action of HP include inhibition of complement activation, reduction of inflammatory responses, and a role in immune regulation. Biologically, HP helps to protect the body from harmful substances produced after haemolysis and maintains iron homeostasis. Its genetic polymorphisms have been associated with the risk of a variety of diseases, including cardiovascular and renal diseases, and it is an important biomarker that guides clinical diagnosis and treatment.
● Recombinant Mouse Haptoglobin (Hp)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
● HP Recombinant Monoclonal Antibody
Validated Data
IHC image of CSB-RA224179A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
IHC image of CSB-RA224179A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following Hp reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Hp Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010691GA01HU | HP Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA14609A0Rb | HP Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA14609B0Rb | HP Antibody, HRP conjugated |
Human | ELISA |
CSB-PA14609C0Rb | HP Antibody, FITC conjugated |
Human | |
CSB-PA14609D0Rb | HP Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA009255 | HP Antibody |
Human | IHC, ELISA |
CSB-PA698087 | HP Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA568452 | HP Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA153691 | HP Antibody |
Human | ELISA,IHC |
CSB-PA790577 | HP Antibody |
Human | ELISA,IHC |
CSB-RA224179A0HU | HP Recombinant Monoclonal Antibody |
Human | ELISA, IHC |
Hp Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010691HU CSB-EP010691HU CSB-BP010691HU CSB-MP010691HU CSB-EP010691HU-B |
Recombinant Human Haptoglobin (HP) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP010691HU | Recombinant Human Haptoglobin (HP) |
E.coli |
CSB-EP010691HUe1 | Recombinant Human Haptoglobin (HP) |
E.coli |
Hp ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08584h | Human Haptoglobin,Hpt/HP ELISA KIT |
serum, plasma, urine | 1.044 ng/mL |