IAPP, also known as islet amyloid polypeptide, is a 37-amino acid polypeptide secreted by pancreatic beta cells, which plays a key role in maintaining blood glucose balance and regulating glucose homeostasis. As an amphipathic polypeptide, the structural characteristics of IAPP make it have certain biological activity under physiological and pathological conditions. In recent years, studies have found that IAPP not only plays a role in the pancreas, but also expresses in human brain tissue, which is closely related to cognitive decline and the occurrence of Alzheimer's disease AD. Although the signaling pathways directly involved in IAPP are not fully understood, it can be speculated that it may indirectly affect signaling pathways related to glucose metabolism, pancreatic function, and inflammatory response. Therefore, the potential role of IAPP in diabetes and neurodegenerative diseases requires further research and exploration.
The following IAPP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IAPP Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA12224D0Rb | IAPP Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA12224B0Rb | IAPP Antibody, HRP conjugated |
Human | ELISA |
CSB-PA12224C0Rb | IAPP Antibody, FITC conjugated |
Human | |
CSB-PA12224A0Rb | IAPP Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA000874 | IAPP Antibody |
Human | WB, IHC, IF, ELISA |
CSB-PA442564 | IAPP Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA949254 | IAPP Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA010931YD01HU | IAPP Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA010931YA01HU | IAPP Antibody |
Human | ELISA |
IAPP Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010931HU | Recombinant Human Islet amyloid polypeptide (IAPP), partial |
Yeast |
CSB-BP010931HU CSB-MP010931HU CSB-EP010931HU-B |
Recombinant Human Islet amyloid polypeptide (IAPP), partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP010931HU | Recombinant Human Islet amyloid polypeptide protein (IAPP), partial |
E.coli |
IAPP ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E09624h | Human islet amyloid polypeptide,IAPP ELISA Kit |
serum, plasma, urine | 11.75 pg/mL |