MLANA, or Melan-A, is a gene that encodes a melanoma antigen in humans. It is located on chromosome 9, band p24.1, and contains multiple transcripts.The proteins expressed by the MLANA gene are predominantly localised to the cell membrane and there is evidence at the protein level to support their expression.MLANA plays an important role in the development and function of melanocytes, and is involved in the regulation of the synthesis of melanin, the pigment that provides colour to the skin, hair and eyes. In addition, the expression of the MLANA gene has been associated with certain types of cancer, particularly melanoma, and changes in its expression level may be correlated with tumour progression and prognosis. Therefore, MLANA is biologically important in the diagnosis and treatment of skin pigmentation and melanoma.
● Recombinant Human Melanoma antigen recognized by T-cells 1 (MLANA)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA621968ESR1HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA621968ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following MLANA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MLANA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA998735 | MLANA Antibody |
Human | ELISA,WB,IHC |
CSB-PA621968ESR1HU | MLANA Antibody |
Human | ELISA, IHC, IF |
CSB-PA621968ESR2HU | MLANA Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA008328 | MLANA Antibody |
Human | WB, IHC, ELISA |
CSB-PA621968LA01HU | MLANA Antibody |
Human | ELISA, WB, IHC |
CSB-PA621968LC01HU | MLANA Antibody, FITC conjugated |
Human |
MLANA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP621968HU | Recombinant Human Melanoma antigen recognized by T-cells 1 (MLANA) |
E.coli |
CSB-YP621968HU | Recombinant Human Melanoma antigen recognized by T-cells 1 (MLANA) |
Yeast |
CSB-BP621968HU CSB-MP621968HU CSB-EP621968HU-B |
Recombinant Human Melanoma antigen recognized by T-cells 1 (MLANA) |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |