SERPINA5, serine protease inhibitor family A member 5, is a protein expressed in human blood and encoded by the SERPINA5 gene. It is a heparin-dependent serine protease inhibitor that functions primarily in body fluids and secretions.SERPINA5 inhibits the activity of serine proteases by irreversibly binding to the active sites of these enzymes. It plays an important role in the regulation of protein hydrolytic activity both inside and outside the vasculature, and is involved in blood coagulation and inflammatory responses. It exerts haemostatic and coagulation-promoting effects through inhibition of anticoagulant factor-activating protein C, as well as coagulation factors, such as thrombospondin, factor XI, factor Xa, and plasma kinin-releasing enzyme. Biologically, abnormal expression of SERPINA5 is associated with a variety of diseases, including thrombosis, epilepsy, hereditary spherocytosis, etc. It is an important molecule in the study of haematological and inflammatory diseases.
Recombinant Mouse Plasma serine protease inhibitor (Serpina5) (CSB-BP021061MO)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SERPINA5 Antibody (CSB-PA021061LA01HU)
Validated Data
Western Blot
Positive WB detected in: Rat liver tissue, Mouse liver tissue
All lanes: SERPINA5 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
Immunohistochemistry analysis of human ovarian cancer using CSB-PA021061LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA021061LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following Serpina5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Serpina5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021061GA01HU | SERPINA5 Antibody |
Human | ELISA,WB,IHC |
CSB-PA561778 | SERPINA5 Antibody |
Human | ELISA,WB |
CSB-PA003700 | SERPINA5 Antibody |
Human | WB, IHC, ELISA |
CSB-PA979705 | SERPINA5 Antibody |
Human | ELISA,WB |
CSB-PA729954 | SERPINA5 Antibody |
Human | ELISA,WB,IHC |
CSB-PA021061LA01HU | SERPINA5 Antibody |
Human, Mouse, Rat | ELISA, WB, IHC, IF |
CSB-PA021061LC01HU | SERPINA5 Antibody, FITC conjugated |
Human | |
CSB-PA021061LD01HU | SERPINA5 Antibody, Biotin conjugated |
Human | ELISA |
Serpina5 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP021061MO CSB-EP021061MO CSB-MP021061MO CSB-EP021061MO-B |
Recombinant Mouse Plasma serine protease inhibitor (Serpina5) |
Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
CSB-BP021061MO | Recombinant Mouse Plasma serine protease inhibitor (Serpina5) |
Baculovirus |
Serpina5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP021061HU CSB-EP021061HU CSB-BP021061HU CSB-MP021061HU CSB-EP021061HU-B |
Recombinant Human Plasma serine protease inhibitor (SERPINA5) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Serpina5 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP868236BO CSB-EP868236BO CSB-BP868236BO CSB-MP868236BO CSB-EP868236BO-B |
Recombinant Bovine Plasma serine protease inhibitor (SERPINA5) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Serpina5 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL021061HU | Human Plasma serine protease inhibitor(SERPINA5) ELISA kit |
serum, plasma, tissue homogenates, cell culture supernates, urine | 0.039 ng/mL |