Transcriptional enhancer factor TEF-5 is a protein in humans that is encoded by TEAD3 gene. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
The following TEAD3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TEAD3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA860344LA01HU | TEAD3 Antibody |
Human | ELISA, IHC |
CSB-PA023365GA01HU | TEAD3 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA904251 | TEAD3 Antibody |
Human | ELISA,WB |
CSB-PA050233 | TEAD3 Antibody |
Human,Mouse | WB, ELISA |
TEAD3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP023365MO CSB-EP023365MO CSB-BP023365MO CSB-MP023365MO CSB-EP023365MO-B |
Recombinant Mouse Transcriptional enhancer factor TEF-5 (Tead3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TEAD3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP838564CH CSB-EP838564CH CSB-BP838564CH CSB-MP838564CH CSB-EP838564CH-B |
Recombinant Chicken Transcriptional enhancer factor TEF-5 (TEAD3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TEAD3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP860344HU CSB-BP860344HU CSB-MP860344HU CSB-EP860344HU-B |
Recombinant Human Transcriptional enhancer factor TEF-5 (TEAD3) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP860344HU | Recombinant Human Transcriptional enhancer factor TEF-5 (TEAD3), partial |
E.coli |