TSLP thymic stromal lymphopoietin is a pleiotropic cytokine belonging to the short-chain four-alpha-helix bundle type I IL-2 family, which is produced by epithelial cells and plays an important role in activating the immune system. TSLP exerts its effects through interaction with its receptor complex, which consists of the TSLP receptor TSLPR and the interleukin 7 receptor alpha chain IL-7Rα, thereby activating downstream signaling pathways. There are two subtypes of TSLP, long-chain lfTSLP and short-chain sfTSLP, which are composed of 159 and 63 amino acids, respectively, and are associated with inflammatory effects and TSLP's homeostatic function. The signaling of TSLP is critical for the maturation and activation of various immune cells, including dendritic cells and innate lymphoid cells 2ILC2, by activating the JAK-STAT5 and PI3K-AKT pathways. TSLP plays a key role in the occurrence and development of allergic diseases such as asthma, atopic dermatitis, food allergy, allergic rhinitis, and chronic obstructive pulmonary disease, and it also shows potential in the field of cancer, such as inhibiting the growth and metastasis of breast tumors. Therefore, TSLP is a potential target for the treatment of allergic diseases and certain cancers, and the regulation of its signaling pathway is important for controlling inflammation and immune responses.
The following TSLP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TSLP Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025141GA01HU | TSLP Antibody |
Human | ELISA,IHC |
CSB-PA218260 | TSLP Antibody |
Human | ELISA,WB |
CSB-PA025141LA01HU | TSLP Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA025141LC01HU | TSLP Antibody, FITC conjugated |
Human | |
CSB-PA025141LD01HU | TSLP Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA025141A1HU | TSLP Recombinant Monoclonal Antibody |
Human | ELISA |
TSLP Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP025141HU CSB-BP025141HU CSB-EP025141HU-B |
Recombinant Human Thymic stromal lymphopoietin (TSLP) |
Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-AP002121HU | Recombinant Human Thymic stromal lymphopoietin protein (TSLP) (Active) |
E.coli |
CSB-MP025141HU | Recombinant Human Thymic stromal lymphopoietin (TSLP) |
Mammalian cell |
CSB-EP025141HU | Recombinant Human Thymic stromal lymphopoietin (TSLP) |
E.coli |
CSB-MP025141HUh8(M) | Recombinant Human Thymic stromal lymphopoietin (TSLP)(R127A,R130A) |
Mammalian cell |
CSB-MP025141HU(M) | Recombinant Human Thymic stromal lymphopoietin (TSLP) (R127A,R130A) |
Mammalian cell |
TSLP Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP025141MO CSB-EP025141MO CSB-BP025141MO CSB-MP025141MO CSB-EP025141MO-B |
Recombinant Mouse Thymic stromal lymphopoietin (Tslp) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TSLP ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E09316h | Human thymic stromal lymphopoietin,TSLP ELISA Kit |
serum, plasma, tissue homogenates. | 0.078 ng/ml |
TSLP ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL025141MO | Mouse Thymic stromal lymphopoietin(TSLP) ELISA kit |
serum, plasma, tissue homogenates | 3.9 pg/ml |