Vacuolar protein sorting-associated protein 4B is a protein in humans that is encoded by VPS4B gene. Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.
The following VPS4B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
VPS4B Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA025915GA01HU | VPS4B Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA025915LA01HU | VPS4B Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA025915LB01HU | VPS4B Antibody, HRP conjugated |
Human | ELISA |
CSB-PA025915LC01HU | VPS4B Antibody, FITC conjugated |
Human | |
CSB-PA025915LD01HU | VPS4B Antibody, Biotin conjugated |
Human | ELISA |
VPS4B Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP025915MO CSB-EP025915MO CSB-BP025915MO CSB-MP025915MO CSB-EP025915MO-B |
Recombinant Mouse Vacuolar protein sorting-associated protein 4B (Vps4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS4B Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP025915HU CSB-EP025915HU CSB-BP025915HU CSB-MP025915HU CSB-EP025915HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 4B (VPS4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS4B Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP613141BO CSB-EP613141BO CSB-BP613141BO CSB-MP613141BO CSB-EP613141BO-B |
Recombinant Bovine Vacuolar protein sorting-associated protein 4B (VPS4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VPS4B Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP722290PYX CSB-EP722290PYX CSB-BP722290PYX CSB-MP722290PYX CSB-EP722290PYX-B |
Recombinant Pongo abelii Vacuolar protein sorting-associated protein 4B (VPS4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |